2-Methoxy-4-picolinic acid
2-Methoxy-4-pyridinecarboxylic acid
CAS: 105596-63-2
Molecular Formula: C7H7NO3
2-Methoxy-4-picolinic acid - Names and Identifiers
| Name | 2-Methoxy-4-pyridinecarboxylic acid |
| Synonyms | 2-METHOXYISONICOTINIC ACID 2-METHOXYISONICOTONIC ACID 2-Methoxy-4-picolinic acid 2-methoxypyridine-4-carboxylate 2-Methoxy-4-pyridinecarboxylic acid 2-METHOXY-4-PYRIDINECARBOXYLIC ACID 4-METHOXY-4-PYRIDINECARBOXYLIC ACID 2-methoxypyridine-4-carboxylic acid 2-METHOXYPYRIDINE-4-CARBOXYLIC ACID 4-Pyridinecarboxylicacid,2-methoxy-(9CI) 2-Methoxy-4-pyridinecarboxylic acid 2-Methoxyisonicotinic acid |
| CAS | 105596-63-2 |
| InChI | InChI=1/C7H7NO3/c1-11-6-4-5(7(9)10)2-3-8-6/h2-4H,1H3,(H,9,10)/p-1 |
| InChIKey | DPNDWFVORIGXQO-UHFFFAOYSA-N |
2-Methoxy-4-picolinic acid - Physico-chemical Properties
| Molecular Formula | C7H7NO3 |
| Molar Mass | 153.14 |
| Density | 1.284±0.06 g/cm3(Predicted) |
| Melting Point | 198-200 °C |
| Boling Point | 383.0±22.0 °C(Predicted) |
| Flash Point | 185.4°C |
| Vapor Presure | 1.5E-06mmHg at 25°C |
| Appearance | Crystalline powder |
| Color | White to pale brown |
| pKa | 4.50±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD04115718 |
2-Methoxy-4-picolinic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
2-Methoxy-4-picolinic acid - Introduction
2-Methoxy-4-picolinic acid is an organic compound with the chemical formula C8H9NO3.
Nature:
-Appearance: White crystalline solid.
-Melting point: about 150-152 ℃.
-Solubility: can be dissolved in water, and better solubility in organic solvents.
Use:
-2-methoxy-4-picolinic acid is mainly used as a pharmaceutical intermediate and has a wide range of applications in the pharmaceutical field.
-It can be used to synthesize various pyridine compounds, such as drugs, pesticides, etc.
Preparation Method:
-2-methoxy-4-picolinic acid can usually be prepared by reacting 2,4-dimethoxy pyridine with sodium nitrite under alkaline conditions. The reaction product can be purified by the process steps of crystallization, filtration and drying.
Safety Information:
-2-methoxy-4-picolinic acid is stable under general conditions, but contact with oxidants and strong acids should be avoided.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing during handling and storage.
-Avoid inhalation, ingestion and contact with skin or eyes during use.
-If necessary, follow local safe practices and waste handling regulations for handling and disposal.
Nature:
-Appearance: White crystalline solid.
-Melting point: about 150-152 ℃.
-Solubility: can be dissolved in water, and better solubility in organic solvents.
Use:
-2-methoxy-4-picolinic acid is mainly used as a pharmaceutical intermediate and has a wide range of applications in the pharmaceutical field.
-It can be used to synthesize various pyridine compounds, such as drugs, pesticides, etc.
Preparation Method:
-2-methoxy-4-picolinic acid can usually be prepared by reacting 2,4-dimethoxy pyridine with sodium nitrite under alkaline conditions. The reaction product can be purified by the process steps of crystallization, filtration and drying.
Safety Information:
-2-methoxy-4-picolinic acid is stable under general conditions, but contact with oxidants and strong acids should be avoided.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing during handling and storage.
-Avoid inhalation, ingestion and contact with skin or eyes during use.
-If necessary, follow local safe practices and waste handling regulations for handling and disposal.
Last Update：2024-04-09 02:00:41
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